GLUCOVANCE 1000/5 30'S

Type 2 Diabetes mellitus: 1-Patients with inadequate glycemic control on diet and exercise alone: Oral: Initial: Glyburide 1.25 mg/metformin 250 mg once or twice daily with meals. 2-Patients with inadequate glycemic control on metformin or glyburide (or another sulfonylurea) monotherapy: Oral: Initial: Glyburide 2.5 mg/metformin 500 mg or glyburide 5 mg/metformin 500 mg twice daily with meals. 3-Dosage adjustments: Oral: Increase dose gradually per glycemic control and tolerability up to a maximum dose of glyburide 20 mg/metformin 2 g per day.